Rheumatoid Arthritis
Rheumatoid Arthritis
What Is Rheumatoid
Arthritis?
Rheumatoid arthritis (RA) is an inflammatory disease that
causes pain, swelling, stiffness, and loss of function in the joints. It occurs
when the immune system, which normally defends the body from invading organisms,
turns its attack against the membrane lining the joints.
Rheumatoid arthritis has several features that make it
different from other kinds of arthritis. For example, rheumatoid arthritis
generally occurs in a symmetrical pattern, meaning that if one knee or hand is
involved, the other one also is. The disease often affects the wrist joints and
the finger joints closest to the hand. It can also affect other parts of the
body besides the joints. In addition, people with rheumatoid arthritis may
have fatigue, occasional fevers, and a general sense of not feeling well.
The course of rheumatoid arthritis can range from mild to
severe. In most cases it is chronic, meaning it lasts a long time often a
lifetime. For many people, periods of relatively mild disease activity are
punctuated by flares, or times of heightened disease activity. In others,
symptoms are constant.
Features of
Rheumatoid Arthritis
- Tender, warm, swollen joints
- Symmetrical pattern of affected joints
- Joint inflammation often affecting the wrist
and finger joints closest to the hand
- Joint inflammation sometimes affecting other
joints, including the neck, shoulders, elbows, hips, knees, ankles, and
feet
- Fatigue, occasional fevers, a general sense of not
feeling well
- Pain and stiffness lasting for more than 30 minutes
in the morning or after a long rest
- Symptoms that last for many years
- Variability of symptoms among people with the disease
Who Has Rheumatoid Arthritis?
Scientists estimate that about 1.3 million people, or about
0.6 percent of the U.S. adult population, have rheumatoid arthritis.
Interestingly, some recent studies have suggested that although the number of
new cases of rheumatoid arthritis for older people is increasing, the overall
number of new cases may actually be going down.
Rheumatoid arthritis occurs in all races and ethnic groups.
Although the disease often begins in middle age and occurs with increased
frequency in older people, children and young adults also develop it. Like some
other forms of arthritis, rheumatoid arthritis occurs much more frequently in
women than in men. About two to three times as many women as men have the
disease.
What Happens in Rheumatoid
Arthritis?
Rheumatoid arthritis is primarily a disease of the joints. A
joint is the point where two or more bones come together. With a few exceptions
(in the skull and pelvis, for example), joints are designed to allow movement
between the bones and to absorb shock from movements like walking or repetitive
motions. The ends of the bones are covered by a tough, elastic tissue called
cartilage. The joint is surrounded by a capsule that protects and supports it.
The joint capsule is lined with a type of tissue called synovium, which produces
synovial fluid, a clear substance that lubricates and nourishes the cartilage
and bones inside the joint capsule.
Like many other rheumatic diseases, rheumatoid arthritis is an
autoimmune disease (auto means self), so-called because a persons
immune system, which normally helps protect the body from infection and disease,
attacks joint tissues for unknown reasons. White blood cells, the agents of the
immune system, travel to the synovium and cause inflammation (synovitis),
characterized by warmth, redness, swelling, and pain typical symptoms of
rheumatoid arthritis. During the inflammation process, the normally thin
synovium becomes thick and makes the joint swollen and puffy to the touch.
As rheumatoid arthritis progresses, the inflamed synovium
invades and destroys the cartilage and bone within the joint. The surrounding
muscles, ligaments, and tendons that support and stabilize the joint become weak
and unable to work normally. These effects lead to the pain and joint damage
often seen in rheumatoid arthritis. Researchers studying rheumatoid arthritis
now believe that it begins to damage bones during the first year or two that a
person has the disease, one reason why early diagnosis and treatment are so
important.
Some people with rheumatoid arthritis also have symptoms in
places other than their joints. Many people with rheumatoid arthritis develop
anemia, or a decrease in the production of red blood cells. Other effects that
occur less often include neck pain and dry eyes and mouth. Very rarely, people
may have inflammation of the blood vessels (vasculitis), the lining of the lungs
(pleurisy), or the sac enclosing the heart (pericarditis).
A joint (the place where two bones meet) is surrounded
by a capsule that protects and supports it. The joint capsule is lined with
a type of tissue called synovium, which produces synovial fluid that
lubricates and nourishes joint tissues. In rheumatoid arthritis, the
synovium becomes inflamed, causing warmth, redness, swelling, and pain. As
the disease progresses, the inflamed synovium invades and damages the
cartilage and bone of the joint. Surrounding muscles, ligaments, and tendons
become weakened. Rheumatoid arthritis also can cause more generalized bone
loss that may lead to osteoporosis (fragile bones that are prone to
fracture).
How Does Rheumatoid Arthritis Affect
People's Lives?
Rheumatoid arthritis affects people differently. For some
people, it lasts only a few months or a year or two and goes away without
causing any noticeable damage. Other people have mild or moderate forms of the
disease, with periods of worsening symptoms, called flares, and periods in which
they feel better, called remissions. Still others have a severe form of the
disease that is active most of the time, lasts for many years or a lifetime, and
leads to serious joint damage and disability.
Although rheumatoid arthritis is primarily a disease of the
joints, its effects are not just physical. Many people with rheumatoid arthritis
also experience issues related to:
- depression, anxiety
- feelings of helplessness
- low self-esteem.
Rheumatoid arthritis can affect virtually every area of a
persons life from work life to family life. One study showed that more than a
quarter of women stopped working within 4 years after being diagnosed with
rheumatoid arthritis. Rheumatoid arthritis can also interfere with the joys and
responsibilities of family life and may affect the decision to have children.
What Causes Rheumatoid Arthritis?
Most conventional researchers still do not know exactly what
causes the immune system to turn against itself in rheumatoid arthritis. Here
are a list of factors conventional doctors believe could be the cause of RA.
Genetic (inherited) factors:
Scientists have discovered that certain genes known to play a role in the immune
system are associated with a tendency to develop rheumatoid arthritis. For the
genes that have been linked to rheumatoid arthritis, the frequency of the risky
gene is only modestly higher in those with rheumatoid arthritis compared with
healthy controls. In other words, individual genes by themselves confer only a
small relative risk of disease. Some people who have these particular genes
never develop the disease. These observations suggest that although a person�s
genetic makeup plays an important role in determining if he or she will develop
rheumatoid arthritis, it is not the only factor. What is clear, however, is that
more than one gene is involved in determining whether a person develops
rheumatoid arthritis and how severe the disease will become.
Environmental factors: Many
scientists think that something must occur to trigger the disease process in
people whose genetic makeup makes them susceptible to rheumatoid arthritis. A
viral or bacterial infection appears likely, but the exact agent is not yet
known. This does not mean that rheumatoid arthritis is contagious: a person
cannot catch it from someone else.
Other factors: Some scientists also
think that a variety of hormonal factors may be involved. Women are more likely
to develop rheumatoid arthritis than men. The disease may improve during
pregnancy and flare after pregnancy. Breastfeeding may also aggravate the
disease. Contraceptive use may alter a person's likelihood of developing
rheumatoid arthritis. This suggests hormones, or possibly deficiencies or
changes in certain hormones, may promote the development of rheumatoid arthritis
in a genetically susceptible person who has been exposed to a triggering agent
from the environment.
How Is Rheumatoid Arthritis
Diagnosed?
Rheumatoid arthritis can be difficult to diagnose in its early
stages for several reasons. First, there is no single test for the disease. In
addition, symptoms differ from person to person and can be more severe in some
people than in others. Also, symptoms can be similar to those of other types of
arthritis and joint conditions, and it may take some time for other conditions
to be ruled out. Finally, the full range of symptoms develops over time, and
only a few symptoms may be present in the early stages. As a result, doctors use
a variety of the following tools to diagnose the disease and to rule out other
conditions:
Medical history: The doctor begins
by asking the patient to describe the symptoms, and when and how the condition
started, as well as how the symptoms have changed over time. The doctor will
also ask about any other medical problems the patient and close family members
have and about any medications the patient is taking. Accurate answers to these
questions can help the doctor make a diagnosis and understand the impact the
disease has on the patient's life.
Good communication between patient and doctor is especially
important. For example, the patient's description of pain, stiffness, and joint
function and how these change over time is critical to the doctor's initial
assessment of the disease and how it changes over time.
Physical examination: The doctor
will check the patient's reflexes and general health, including muscle strength.
The doctor will also examine bothersome joints and observe the patient's ability
to walk, bend, and carry out activities of daily living. The doctor will also
look at the skin for a rash and listen to the chest for signs of inflammation in
the lungs.
Laboratory tests: A number of lab
tests may be useful in confirming a diagnosis of rheumatoid arthritis. Following
are some of the more common ones:
-
Rheumatoid factor (RF): Rheumatoid factor
is an antibody that is present eventually in the blood of most people with
rheumatoid arthritis. (An antibody is a special protein made by the immune
system that normally helps fight foreign substances in the body.) Not all
people with rheumatoid arthritis test positive for rheumatoid factor, and
some people test positive for rheumatoid factor, yet never develop the
disease. Rheumatoid factor also can be positive in some other diseases;
however, a positive RF in a person who has symptoms consistent with those of
rheumatoid arthritis can be useful in confirming a diagnosis. Furthermore,
high levels of rheumatoid factor are associated with more severe rheumatoid
arthritis.
Anti-CCP antibodies: This blood test
detects antibodies to cyclic citrullinated peptide (anti-CCP). This test is
positive in most people with rheumatoid arthritis and can even be positive
years before rheumatoid arthritis symptoms develop. When used with the RF,
this test's results are very useful in confirming a rheumatoid arthritis
diagnosis.
Others: Other common laboratory tests
include a white blood cell count, a blood test for anemia, which is common
in rheumatoid arthritis; the erythrocyte sedimentation rate (often called
the sed rate), which measures inflammation in the body; and C-reactive
protein, another common test for inflammation that is useful both in making
a diagnosis and monitoring disease activity and response to
anti-inflammatory therapy.
X rays: X rays are used to determine
the degree of joint destruction. They are not useful in the early stages of
rheumatoid arthritis before bone damage is evident; however, they may be used to
rule out other causes of joint pain. They may also be used later to monitor the
progression of the disease.
The Dangers of Conventional Drug Therapies
The traditional treatment for RA involves drugs. Lots of dangerous drugs. But
did you know that aspirin and other over-the-counter drugs can put you in the
hospital or under the ground! Every doctor who was awake during medical classes
in college knows the dangers of NSAIDs (non-steroidal anti-inflammatory drugs).
They know for example, that aspirin causes the lining of the stomach to bleed
and that it burns tiny holes into your gastrointestinal tract. You may lose up
to one teaspoon of blood each time you take a standard dose of aspirin (more if
you are at risk for bleeding or consume more than the standard dose) Sadly, the
reality is that NSAIDs do more than just cause gastrointestinal problems. They
kill over 10,000 people a year and are the cause of over 76,000 hospitalizations
annually.
According to author, Dr. Earl Mindell, NSAIDs interfere with the body's ability
to repair cartilage. And research has shown that they accelerate the progression
of osteoarthritis. Says Mindell, Even if NSAIDs didn't cause such serious
problems, they can cause a more subtle condition called leaky gut. This is a
condition that causes tiny holes to erode the intestinal wall, allowing partly
digested food and toxins to enter into the bloodstream. Of course, once these
wastes and toxins breach the intestinal wall, your immune system begins
attacking them. This puts tremendous stress on the immune system. This leaky gut
condition then sets the stage for the development of other diseases such as
rheumatoid arthritis, allergies, and asthma.
Alternate Approach
to Treating This Disease
Arthritis in general is nothing more than a motley crew of
nutritional deficiencies. In the case of rheumatoid arthritis, many naturopathic
doctors agree that its primary cause is a chronic infection by a mycoplasma.
Noted naturopath, Dr. Joel Wallach, states that a specific mycoplasma,
mycoplasma spp, is the primary culprit. Quoting Dr. Wallach, If the truth were
released [to the public], the orthodox doctors wold lose an entire specialty [rheumalogy]
in short order, so they keep it a secret.
In fact, a brilliant doctor over 50 years ago pioneered
eliminating this mycoplasm to get rid of rheumatoid arthritis in his patients.
Yet very few people know of his work although it was published widely in medical
journals. We will talk more about him later and how he cured his patients.
Now here is the protocol used by Dr. Joel Wallach on his
patients. I have augmented it to incorporate my ENDD principles. Pay special
attention to my notes in red:
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